Identifying the Mechanisms of Action of a Novel 8-Hydroxy Quinazolinone in Models of Parkinson's Disease

Grant number: 1043992 | Funding period: 2013 - 2015

Completed

Abstract

By the time symptoms of Parkinson's disease (PD) appear, 60-70% of the cells in a crucial part of the brain called the substantia nigra have been destroyed and within a few years of diagnosis, most of the remaining cells have died. This project investigates the causes of this cell loss and a how a new class of compounds could interrupts the process. Success in achieving the aims of this proposal will add to our knowledge of the causes of neuronal death in PD

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University of Melbourne Researchers

David Finkelstein